SCHEMBL3083718

SCHEMBL3083718

CCNc1ccc(C(=O)OCC)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.63
RECQL P46063 1/20 0.63
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA12 O43570 1/20 0.61
ESR1 P03372 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
ESR2 Q92731 1/20 0.61
CA14 Q9ULX7 1/20 0.61
TSHR P16473 1/20 0.61
RAB9A P51151 7/20 0.60
NPC1 O15118 3/20 0.60
MAPT P10636 3/20 0.60
ALDH1A1 P00352 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
GAA P10253 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735668 0.92 HPGD (0.63) HPGDRECQLCA1CA2CA12
SCHEMBL9804183 0.89 HPGD (0.63) HPGDRECQLCA1CA2CA12
SCHEMBL7101006 0.86 MAPT (0.60) HPGDRECQLCA1CA2CA12
SCHEMBL13444627 0.86 LMNA (0.61) HPGDRECQLCA1CA2CA12
SCHEMBL12652047 0.86 HPGD (0.59) HPGDRECQLCA1CA2CA12
SCHEMBL1798924 0.85 POLB (0.64) HPGDCA1CA2CA12CA7
SCHEMBL12124929 0.85 RAB9A (0.69) HPGDRECQLCA1CA2CA12
SCHEMBL6373144 0.84 MAPT (0.59) HPGDRECQLCA1CA2CA12
SCHEMBL7338663 0.84 TSHR (0.65) HPGDRECQLCA1CA2CA12
SCHEMBL4286423 0.84 HPGD (0.58) HPGDRECQLCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179243-A1 MAIN CHAIN POLYMER, OPTICAL FILM, METHOD FOR PRODUCING MAIN CHAIN POLYMER, METHOD FOR PRODUCING OPTICAL FILM, AND MULTILAYER FILM TOSOH CORPORATION (JP) 2025-06-05 US disclosed
EP-4455128-A1 MAIN CHAIN POLYMER, OPTICAL FILM, METHOD FOR PRODUCING MAIN CHAIN POLYMER, METHOD FOR PRODUCING OPTICAL FILM, AND MULTILAYER FILM Tosoh Corporation (JP) 2024-10-30 EP disclosed
WO-2023120638-A1 MAIN CHAIN POLYMER, OPTICAL FILM, METHOD FOR PRODUCING MAIN CHAIN POLYMER, METHOD FOR PRODUCING OPTICAL FILM, AND MULTILAYER FILM 東ソー株式会社 2023-06-29 WO disclosed
EP-2172450-B9 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-08 EP disclosed
EP-2172450-B9 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2014-10-08 EP disclosed
CN-101784520-B Novel malonic acid sulfonamide derivative and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORP 2014-07-02 CN disclosed
EP-2172450-B1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2013-10-16 EP disclosed
EP-2172450-B1 NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2013-10-16 EP disclosed
US-8461209-B2 Malonic acid sulfonamide derivative and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2013-06-11 US disclosed
US-20130053423-A1 Cosmetic Use of Substituted Amino Heterocylic Carbamoyl Analogs and Related Compounds AVON PRODUCTS, INC. (US) 2013-02-28 US disclosed
US-5843942-A Aromatic amino ethers as pain relieving agents ZENECA LIMITED (GB) 1998-12-01 US disclosed
US-5834468-A ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES ZENECA LIMITED (GB) 1998-11-10 US disclosed
WO-1997028123-A1 DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 1997-08-07 WO disclosed
CN-1154106-A Aromatic amino ethers as analgesic agents ZENECA LTD (GB) 1997-07-09 CN disclosed
EP-0773930-A1 AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS ZENECA LIMITED (GB) 1997-05-21 EP disclosed
EP-0752421-A1 Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists ZENECA LIMITED (GB) 1997-01-08 EP disclosed
WO-1996003380-A1 AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS ZENECA LIMITED (GB) 1996-02-08 WO disclosed
US-4273708-A Carbonyl-substituted cyan azo dye-providing materials EASTMAN KODAK COMPANY (US) 1981-06-16 US disclosed
US-4195993-A AZO DYES EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4132774-A SUNSCREEN AGENTS GAF CORPORATION (US) 1979-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053423-A1 Cosmetic Use of Substituted Amino Heterocylic Carbamoyl Analogs and Related Compounds AADAC, GLA, TYR HPGD 223/4885RECQL 1703/4885CA1 4250/4885
US-20250179243-A1 MAIN CHAIN POLYMER, OPTICAL FILM, METHOD FOR PRODUCING MAIN CHAIN POLYMER, METHOD FOR PRODUCING OPTICAL FILM, AND MULTILAYER FILM C9, RNF4, F12 HPGD 4272/4885RECQL 571/4885CA1 3090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.