SCHEMBL9804183

SCHEMBL9804183

CCOC(=O)c1ccc(NCNc2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.63
RECQL P46063 1/20 0.63
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA12 O43570 1/20 0.61
ESR1 P03372 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
ESR2 Q92731 1/20 0.61
CA14 Q9ULX7 1/20 0.61
TSHR P16473 1/20 0.61
RAB9A P51151 7/20 0.60
NPC1 O15118 3/20 0.60
MAPT P10636 3/20 0.60
ALDH1A1 P00352 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
GAA P10253 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3083718 0.89 HPGD (0.63) HPGDRECQLCA1CA2CA12
SCHEMBL13444627 0.86 LMNA (0.61) HPGDRECQLCA1CA2CA12
SCHEMBL7101006 0.86 MAPT (0.60) HPGDRECQLCA1CA2CA12
SCHEMBL12652047 0.86 HPGD (0.59) HPGDRECQLCA1CA2CA12
SCHEMBL12124929 0.85 RAB9A (0.69) HPGDRECQLCA1CA2CA12
SCHEMBL6373144 0.84 MAPT (0.59) HPGDRECQLCA1CA2CA12
SCHEMBL4286423 0.84 HPGD (0.58) HPGDRECQLCA1CA2CA12
SCHEMBL7338663 0.84 TSHR (0.65) HPGDRECQLCA1CA2CA12
SCHEMBL87450 0.84 CA1 (0.83) HPGDRECQLCA1CA2CA12
SCHEMBL3233695 0.83 HPGD (0.65) HPGDRECQLCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925241-A Preservative for cosmetics and preparation process thereof 利洁士医疗器械(重庆)有限公司 2025-05-06 CN claimed
US-11872212-B2 Self-healing organic crystals INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) KOLKATA (IN) 2024-01-16 US claimed
JP-3095147-A None JP disclosed
US-12612395-B2 Rocaglate derivatives and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 2026-04-28 US disclosed
EP-4684019-A2 DENDRITIC CONJUGATES FOR THE BRAIN DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES University of Massachusetts (US) 2026-01-28 EP disclosed
EP-3708167-B1 IMMUNOMODULATING TREATMENTS OF BODY CAVITIES UROGEN PHARMA LTD (IL) 2026-01-28 EP disclosed
US-12508271-B2 Prodrugs of 2-PMPA for healthy tissue protection during PSMA-targeted cancer imaging or radiotherapy THE JOHNS HOPKINS UNIVERSITY (US) 2025-12-30 US disclosed
CN-111670199-B Monoclonal antibody NEO-201 for treating human carcinoma 精密生物制品股份有限公司 2025-06-17 CN disclosed
EP-2877854-B2 FGFR-TACC FUSION PROTEINS AND METHODS THEREOF UNIV COLUMBIA (US) 2025-06-04 EP disclosed
CN-119979609-A Plant source compound target identification method acting on insect 5-hydroxytryptamine receptor 浙江大学 2025-05-13 CN disclosed
CN-119925241-A Preservative for cosmetics and preparation process thereof 利洁士医疗器械(重庆)有限公司 2025-05-06 CN disclosed
US-20230105186-A1 Nanoparticle Modification of Human Adipose-Derived Mesenchymal Stem Cells for Treating Brain Cancer and Other Neurological Diseases JOHNS HOPKINS UNIVERSITY 2023-04-06 US disclosed
US-20230051178-A1 Self-Healing Organic Crystals INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) KOLKATA (IN) 2023-02-16 US disclosed
US-11547729-B2 Nanoparticle modification of human adipose-derived mesenchymal stem cells for treating brain cancer and other neurological diseases THE JOHNS HOPKINS UNIVERSITY (US) 2023-01-10 US disclosed
CN-115335030-A Pigment comprising radish extract and montmorillonite 奇华顿股份有限公司 2022-11-11 CN disclosed
CN-115305241-A Method for quickly and effectively obtaining high-purity glioma stem cell culture 韩欣欣 2022-11-08 CN disclosed
EP-2877854-B1 FGFR-TACC FUSION PROTEINS AND METHODS THEREOF UNIV COLUMBIA (US) 2022-09-07 EP disclosed
US-11414468-B2 Factor B and C2 protein point mutants, a method for enhancing the activity of anti-cancer antibodies, the pharmaceutical composition and the use of mutants GDANSKI UNIWERSYTET MEDYCZNY (PL) 2022-08-16 US disclosed
US-11407991-B2 Nucleic acid extraction from heterogeneous biological materials EXOSOME DIAGNOSTICS, INC. (US) 2022-08-09 US disclosed
JP-H0395147-A MOLECULAR CRYSTAL MIYATA SEIZO 1991-04-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11872212-B2 Self-healing organic crystals DNAJA1, DNAJA3, LIG4 HPGD 3639/4885RECQL 376/4885CA1 2997/4885
US-12612395-B2 Rocaglate derivatives and uses thereof GLRB, SRR, HCAR3 HPGD 1791/4885RECQL 3160/4885CA1 1149/4885
US-20230051178-A1 Self-Healing Organic Crystals DNAJA1, DNAJA3, LIG4 HPGD 3639/4885RECQL 376/4885CA1 2997/4885
US-12508271-B2 Prodrugs of 2-PMPA for healthy tissue protection during PSMA-targeted cancer imaging or radiotherapy KLK3, CTSA, PTMA HPGD 2692/4885RECQL 3883/4885CA1 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.