Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399096 | 0.81 | MMP9 (0.52) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL27956302 | 0.77 | AOC3 (0.62) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10399117 | 0.74 | AOC3 (0.56) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10400885 | 0.74 | AOC3 (0.56) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL11255630 | 0.73 | AOC3 (0.62) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10438325 | 0.71 | ERN1 (0.36) | AOC3MEN1CYP1A2KMT2AHDAC8 | |
| SCHEMBL10400854 | 0.70 | AOC3 (0.57) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10400048 | 0.69 | UGT2B7 (0.55) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL16174482 | 0.68 | AOC3 (0.54) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20976148 | 0.68 | UGT2B7 (0.62) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895861-A | Novel naphthalenyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |