Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399118 | 0.81 | AOC3 (0.52) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL10400048 | 0.76 | UGT2B7 (0.55) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL2203728 | 0.76 | FFAR1 (0.57) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL17451237 | 0.75 | UGT2B7 (0.50) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL6678170 | 0.74 | ABCB11 (0.66) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL6678168 | 0.74 | UGT2B7 (0.57) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL27989030 | 0.74 | TNF (0.56) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL27980860 | 0.74 | TNF (0.56) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL6172465 | 0.74 | TNF (0.56) | MMP9UGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL7677411 | 0.73 | UGT2B7 (0.51) | MMP9UGT2B7MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393940-A1 | Substituted and unsubstituted naphthalenyl-3H-1,2,3,5-oxthiadiazole 2-oxides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-24 | — | — | EP | disclosed |
| US-4895861-A | Novel naphthalenyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |