Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398891 | 1.00 | MAOB (0.51) | MAOBGAACES2CES1MAPT | |
| SCHEMBL10398890 | 1.00 | MAOB (0.51) | MAOBGAACES2CES1MAPT | |
| SCHEMBL10399169 | 0.88 | MAOB (0.50) | MAOBGAAMAPTKMT2AMEN1 | |
| SCHEMBL10399170 | 0.88 | MAOB (0.50) | MAOBGAAMAPTKMT2AMEN1 | |
| SCHEMBL10399168 | 0.88 | MAOB (0.50) | MAOBGAAMAPTKMT2AMEN1 | |
| SCHEMBL10399114 | 0.87 | ABCG2 (0.50) | MAOBGAAMAPTNPC1RAB9A | |
| SCHEMBL10399112 | 0.87 | ABCG2 (0.50) | MAOBGAAMAPTNPC1RAB9A | |
| Bicarbonate SCHEMBL9521090 | 0.87 | MAOB (0.48) | MAOBGAACES2CES1MAPT | |
| Bicarbonate SCHEMBL9521138 | 0.87 | MAOB (0.48) | MAOBGAACES2CES1MAPT | |
| SCHEMBL10398296 | 0.86 | CES2 (0.57) | MAOBGAACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |