Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.56 |
| ▸ | PTAFR | P25105 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399198 | 1.00 | TBXAS1 (0.56) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL9522892 | 0.96 | TBXAS1 (0.58) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL10398649 | 0.85 | TBXAS1 (0.59) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL10398650 | 0.85 | TBXAS1 (0.59) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL9709457 | 0.83 | TBXAS1 (0.64) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL3252245 | 0.83 | GRIK1 (0.51) | — | |
| SCHEMBL10398952 | 0.82 | TBXAS1 (0.62) | TBXAS1TDP1L3MBTL1KDM4ECYP2A6 | |
| SCHEMBL9522362 | 0.81 | TBXAS1 (0.61) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL27534729 | 0.80 | TBXAS1 (0.62) | TBXAS1PTAFRTDP1L3MBTL1KDM4E | |
| SCHEMBL9522427 | 0.79 | TBXAS1 (0.63) | TBXAS1PTAFRTDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4927838-A | CARDIOVASCULAR DISORDERS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4927826-A | Cycloproylpropenamides useful as platelet activing factor (PAF) antagonists | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4786646-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-22 | — | — | US | disclosed |