Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399282 | 1.00 | MAOA (0.46) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10399220 | 1.00 | MAOA (0.46) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10399068 | 0.94 | PTAFR (0.47) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10399067 | 0.94 | PTAFR (0.47) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10399066 | 0.94 | PTAFR (0.47) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10399215 | 0.93 | KDM4E (0.43) | MAOAMAOBKDM4EMAPTKMT2A | |
| SCHEMBL10399212 | 0.93 | KDM4E (0.43) | MAOAMAOBKDM4EMAPTKMT2A | |
| SCHEMBL10398876 | 0.88 | MAOB (0.52) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10398878 | 0.88 | MAOB (0.52) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL10398874 | 0.88 | MAOB (0.52) | MAOAMAOBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |