Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399215 | 1.00 | KDM4E (0.43) | KDM4EPOLBGPR17P2RY2MAPT | |
| SCHEMBL10399068 | 0.93 | PTAFR (0.47) | KDM4EMAPTKMT2AGAAPTAFR | |
| SCHEMBL10399067 | 0.93 | PTAFR (0.47) | KDM4EMAPTKMT2AGAAPTAFR | |
| SCHEMBL10399282 | 0.93 | MAOA (0.46) | KDM4EMAPTKMT2AGAAPGR | |
| SCHEMBL10399283 | 0.93 | MAOA (0.46) | KDM4EMAPTKMT2AGAAPGR | |
| SCHEMBL10399220 | 0.93 | MAOA (0.46) | KDM4EMAPTKMT2AGAAPGR | |
| SCHEMBL10399066 | 0.93 | PTAFR (0.47) | KDM4EMAPTKMT2AGAAPTAFR | |
| SCHEMBL10399270 | 0.89 | CES2 (0.49) | KDM4EMAPTKMT2AGAAPTAFR | |
| SCHEMBL10397707 | 0.89 | CES2 (0.49) | KDM4EMAPTKMT2AGAAPTAFR | |
| SCHEMBL10399221 | 0.87 | LMNA (0.45) | KDM4EMAPTPKMKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |