Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 0.67 |
| ▸ | HTR2A | P28223 | 7/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394771 | 0.85 | DRD3 (0.50) | DRD3HTR2AHTR1AKCNH2ADRA2A | |
| SCHEMBL9272319 | 0.82 | HTR1A (0.67) | HTR2AHTR1ADRD2 | |
| SCHEMBL9213659 | 0.82 | DRD3 (0.51) | DRD3HTR2AHTR1AKCNH2ADRA2A | |
| Hydrochloric Acid SCHEMBL9391525 | 0.82 | — | — | |
| SCHEMBL4523269 | 0.81 | HTR1A (1.00) | DRD3HTR2AHTR1AHTR2C | |
| SCHEMBL1039928 | 0.80 | DRD3 (1.00) | DRD3HTR2AHTR1AKCNH2ADRA2A | |
| SCHEMBL13160196 | 0.79 | DRD3 (0.65) | DRD3HTR2AHTR1AHTR2CDRD2 | |
| SCHEMBL31061220 | 0.78 | DRD3 (0.84) | DRD3HTR2AHTR1AHTR2CDRD2 | |
| SCHEMBL4523984 | 0.77 | DRD3 (1.00) | DRD3HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL4527831 | 0.77 | DRD3 (1.00) | DRD3HTR2AHTR1AKCNH2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081907-B1 | ARYL PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROPSYCHIATRY DISORDERS | UNIV SIENA (IT) | 2011-01-26 | — | — | EP | claimed |