Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.48 |
| ▸ | NOS3 | P29474 | 6/20 | 0.48 |
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717960 | 0.85 | NOS2 (0.57) | NOS2NOS3NOS1HRH4ADORA2A | |
| SCHEMBL2717428 | 0.85 | NOS2 (0.48) | NOS2NOS3NOS1HRH4ADORA2A | |
| SCHEMBL4586148 | 0.84 | NOS2 (0.41) | NOS2NOS3NOS1HRH4MAPT | |
| SCHEMBL22623613 | 0.84 | NOS2 (0.41) | NOS2NOS3NOS1HRH4ADORA2A | |
| SCHEMBL20919369 | 0.80 | HRH4 (0.43) | NOS2NOS3NOS1HRH4 | |
| SCHEMBL27874753 | 0.80 | NOS3 (0.38) | NOS2NOS3NOS1HRH4RAB9A | |
| SCHEMBL11802553 | 0.74 | HRH4 (0.34) | HRH4ADORA2AADORA1 | |
| SCHEMBL28396250 | 0.74 | NOS2 (0.36) | NOS2NOS3NOS1MAPTTDP1 | |
| SCHEMBL15994399 | 0.73 | HRH4 (0.52) | NOS2NOS3NOS1HRH4ADORA2A | |
| SCHEMBL10264859 | 0.72 | NOS2 (0.48) | NOS2NOS3NOS1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |