Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.66 |
| ▸ | APP | P05067 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699890 | 1.00 | MAOB (0.66) | MAOBAPPLMNACYP1A2PTGS1 | |
| SCHEMBL8929713 | 0.91 | MAOB (0.69) | MAOBAPPPARP10NPC1RAB9A | |
| SCHEMBL762195 | 0.91 | MAOB (0.69) | MAOBAPPPARP10NPC1RAB9A | |
| SCHEMBL891195 | 0.91 | MAOB (0.69) | MAOBAPPPARP10NPC1RAB9A | |
| SCHEMBL8930213 | 0.91 | MAOB (0.69) | MAOBAPPPARP10NPC1RAB9A | |
| SCHEMBL5633306 | 0.89 | APP (0.79) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL11578826 | 0.89 | APP (0.79) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL420238 | 0.87 | MAOB (0.56) | MAOBAPPLMNACYP1A2PTGS1 | |
| SCHEMBL4054115 | 0.86 | MAOB (0.64) | MAOBAPPLMNAPARP10NPC1 | |
| SCHEMBL8991100 | 0.86 | MAOB (0.64) | MAOBAPPLMNAPARP10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952661-A | AND DICARBOXYLIC AROMATIC ACID, AND OPTIONALLY A HYDROQUINONE; ANISOTROPIC | MONTEDISON S.P.A. (IT) | 1990-08-28 | — | — | US | claimed |
| EP-0300752-A2 | Thermotropic liquid crystalline polyesters | Montedison S.p.A. (IT) | 1989-01-25 | — | — | EP | claimed |
| US-7534547-B2 | Optically active compound and photosensitive resin composition | OSAKA GAS COMPANY LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |