SCHEMBL762195

SCHEMBL762195

Cc1ccc(COc2ccc(C)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.69
PARP10 Q53GL7 1/20 0.67
NPC1 O15118 3/20 0.65
RAB9A P51151 3/20 0.65
CASP3 P42574 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
SENP8 Q96LD8 1/20 0.65
SENP7 Q9BQF6 1/20 0.65
SENP6 Q9GZR1 1/20 0.65
ALDH1A1 P00352 1/20 0.62
MAPT P10636 1/20 0.62
MAPK1 P28482 1/20 0.62
HRH3 Q9Y5N1 1/20 0.62
APP P05067 4/20 0.60
AGXT P21549 2/20 0.56
KCNH2 Q12809 1/20 0.53
MAOA P21397 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8929713 1.00 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL8930213 1.00 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL891195 1.00 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL24701846 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL11853089 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL1702909 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL13637020 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL18635916 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL12918621 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL16603392 0.93 MAOB (0.62) MAOBPARP10NPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043626-A1 METHOD FOR THE SELECTIVE CLEAVAGE OF A COMPOUND COMPRISING AN AROMATIC RING AND A C-O-C LINKAGE RHODIA OPERATIONS (FR) 2024-02-08 US disclosed
EP-4259596-A1 METHOD FOR SELECTIVE CLEAVAGE OF COMPOUND COMPRISING AROMATIC RING AND C-O-C LINKAGE SPECIALTY OPERATIONS FRANCE (FR) 2023-10-18 EP disclosed
CN-116648443-A Method for selectively cleaving a compound comprising an aromatic ring and a C-O-C linkage 罗地亚经营管理公司 2023-08-25 CN disclosed
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2023-07-11 US disclosed
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2023-07-11 US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 US disclosed
WO-2022126310-A1 METHOD FOR SELECTIVE CLEAVAGE OF COMPOUND COMPRISING AROMATIC RING AND C-O-C LINKAGE RHODIA OPERATIONS (FR) 2022-06-23 WO disclosed
EP-3760633-B1 OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2021-12-15 EP disclosed
US-10988692-B2 Liquid crystal medium and liquid crystal device MERCK PATENT GMBH (DE) 2021-04-27 US disclosed
US-20210093691-A1 Glycopeptide Compounds Having Activity Of Resisting Drug-Resistant Bacteria, And Preparation Method And Application Thereof SHANGHAI LAIYI CENTER FOR BIOPHARMACEUTICAL R&D CO., LTD. (CN) 2021-04-01 US disclosed
US-20070054195-A1 Optical recording medium, method of producing the same, and, optical recording method and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-20070047421-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047421-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047419-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047419-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
EP-0946478-B1 PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS AVENTIS PHARMA INC (US) 2007-02-14 EP disclosed
US-4113782-A CATALYTIC OXIDATION AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1978-09-12 US disclosed
US-3968320-A Dye solvents for pressure-sensitive record material MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240043626-A1 METHOD FOR THE SELECTIVE CLEAVAGE OF A COMPOUND COMPRISING AN AROMATIC RING AND A C-O-C LINKAGE AOC2, AOC1, AOC3 MAOB 10/4885PARP10 2652/4885NPC1 1827/4885
US-20210093691-A1 Glycopeptide Compounds Having Activity Of Resisting Drug-Resistant Bacteria, And Preparation Method And Application Thereof VIP, CUTA, MGAM MAOB 2702/4885PARP10 2335/4885NPC1 1225/4885
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 MAOB 1599/4885PARP10 1240/4885NPC1 165/4885
US-11696937-B2 Glycopeptide compounds having activity of resisting drug-resistant bacteria, and preparation method and application thereof VIP, CUTA, MGAM MAOB 2702/4885PARP10 2335/4885NPC1 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.