SCHEMBL8991100

SCHEMBL8991100

Cc1ccc(COc2ccc(CO)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.64
PARP10 Q53GL7 1/20 0.62
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
CASP3 P42574 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.58
HRH3 Q9Y5N1 2/20 0.54
APP P05067 3/20 0.50
FFAR1 O14842 2/20 0.49
LMNA P02545 1/20 0.48
LTA4H P09960 1/20 0.47
EPHX2 P34913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4054115 1.00 MAOB (0.64) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL260484 0.94 MAOB (0.58) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL891195 0.89 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL762195 0.89 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL8930213 0.89 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL8929713 0.89 MAOB (0.69) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL10399449 0.86 MAOB (0.66) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL21699890 0.86 MAOB (0.66) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL9125234 0.85 MAOB (0.60) MAOBPARP10NPC1RAB9ACASP3
SCHEMBL18637175 0.84 RXRA (0.64) PARP10NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4146 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036870-A Antibacterial peptide humAMP, polynucleotide, expression vector, host cell, preparation method and application thereof 河北省科学院生物研究所 2026-05-15 CN claimed
CN-122036872-A Antibacterial peptide humAMP, polynucleotide, expression vector, host cell, preparation method and application thereof 河北省科学院生物研究所 2026-05-15 CN claimed
CN-121405779-B Polypeptide material for expelling solvent, preparation method thereof and application of polypeptide material in preparation of spherical propellant powder 中国兵器工业火炸药工程与安全技术研究院 2026-05-15 CN claimed
CN-122036871-A Antibacterial peptide humAMP and polynucleotide, expression vector, host cell, preparation method and application thereof 河北省科学院生物研究所 2026-05-15 CN claimed
CN-122036873-A Antibacterial peptide humAMP and polynucleotide, expression vector, host cell, preparation method and application thereof 河北省科学院生物研究所 2026-05-15 CN claimed
CN-122011107-A Polypeptide, preparation method thereof and application thereof in delaying muscle attenuation 内蒙古蒙牛乳业(集团)股份有限公司 2026-05-12 CN claimed
CN-122029186-A Human growth hormone receptor antagonists and methods of use thereof OPKO生物科学有限公司 2026-05-12 CN claimed
US-12565518-B2 Hybrid cyclic libraries and screens thereof THE JOHNS HOPKINS UNIVERSITY (US) 2026-03-03 US claimed
US-20260042810-A1 A PROCESS FOR THE PREPARATION OF GLUCAGON BIOCON LTD (IN) 2026-02-12 US claimed
US-20250387498-A1 CELL-PENETRATING PEPTIDES UNIV OXFORD INNOVATION LTD (GB) 2025-12-25 US claimed
CN-113956333-B Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-03-29 CN claimed
CN-113214354-B Modified nonapeptide and preparation method and application thereof 北京北科华夏生物医药科技有限公司 2022-03-25 CN claimed
CN-110294800-B Preparation method of somaglutide 齐鲁制药有限公司 2022-03-04 CN claimed
CN-113845587-B Synthetic method of bivalirudin 浙江湃肽生物有限公司南京分公司 2022-02-18 CN claimed
CN-114044813-A Preparation and purification method of procatide 浙江湃肽生物有限公司南京分公司 2022-02-15 CN claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US claimed
CN-114014912-A Method for preparing leuprorelin by combining solid phase and liquid phase 浙江湃肽生物有限公司南京分公司 2022-02-08 CN claimed
US-20220033440-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PLECANATIDE ENZENE BIOSCIENCES LIMITED (IN) 2022-02-03 US claimed
CN-113968902-A Leucine-enkephalin analogue and preparation method and application thereof 兰州大学 2022-01-25 CN claimed
CN-113956333-A Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-01-21 CN claimed