Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992731 | 0.89 | KDM4E (0.33) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL9051200 | 0.89 | KDM4E (0.33) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL28586804 | 0.85 | CD44 (0.33) | PPARA | |
| SCHEMBL10477482 | 0.77 | CHRNB2 (0.33) | CYP3A4CASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL511920 | 0.76 | DPP4 (0.42) | SMN1; SMN2GAAKDM4EALDH1A1MEN1 | |
| SCHEMBL13953886 | 0.76 | KDM1A (0.42) | CYP3A4GAAKDM4EPPARAMEN1 | |
| SCHEMBL16755274 | 0.76 | ALDH1A1 (0.42) | CYP3A4SMN1; SMN2GAAMAPTPPARA | |
| SCHEMBL16398268 | 0.76 | HTR2C (0.44) | HTR2A | |
| SCHEMBL16398264 | 0.76 | HTR2C (0.44) | HTR2A | |
| SCHEMBL8625311 | 0.76 | MEN1 (0.42) | CYP3A4ALOX15SMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935053-A | Unsaturated haloacetanilides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-19 | — | — | US | disclosed |