Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186353 | 0.91 | RCE1 (0.56) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL1901574 | 0.89 | RCE1 (0.52) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL4467147 | 0.89 | RCE1 (0.52) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL10398283 | 0.86 | RCE1 (0.53) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL6901088 | 0.86 | RCE1 (0.53) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL10399412 | 0.85 | LMNA (0.56) | RCE1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL14544524 | 0.82 | LPAR1 (0.67) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28107769 | 0.82 | MEN1 (0.61) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL13708399 | 0.81 | HDAC1 (0.52) | RCE1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL12449247 | 0.80 | FOLH1 (0.48) | MEN1KMT2AHDAC1HDAC6FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |