Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.47 |
| ▸ | GLI2 | P10070 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186353 | 0.92 | RCE1 (0.56) | RCE1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL10398283 | 0.88 | RCE1 (0.53) | RCE1MAPTMEN1NPC1RAB9A | |
| SCHEMBL10399412 | 0.86 | LMNA (0.56) | RCE1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL10399486 | 0.86 | RCE1 (0.52) | RCE1MAPTMEN1NPC1RAB9A | |
| SCHEMBL14544524 | 0.84 | LPAR1 (0.67) | MAPTKDM4EMEN1NPC1RAB9A | |
| SCHEMBL28107769 | 0.83 | MEN1 (0.61) | RCE1MAPTMEN1NPC1RAB9A | |
| SCHEMBL12018645 | 0.81 | L3MBTL1 (0.49) | RCE1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30725590 | 0.81 | L3MBTL1 (0.52) | RCE1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9416644 | 0.81 | ALDH1A1 (0.50) | KDM4ECA2 | |
| SCHEMBL6540922 | 0.81 | L3MBTL1 (0.48) | RCE1KDM4EMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900241-B1 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| US-6127489-A | Silyl linker for solid phase organic synthesis of aryl-containing molecules | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |