SCHEMBL10399684

SCHEMBL10399684

CN(CCCl)CC(=O)C1CCCCCN1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 1/20 0.34
PRCP P42785 1/20 0.33
MAPT P10636 2/20 0.32
GLI1 P08151 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
LMNA P02545 2/20 0.31
TP53 P04637 2/20 0.31
HTT P42858 2/20 0.31
TSHR P16473 1/20 0.31
HBB P68871 1/20 0.31
ADRA2A P08913 1/20 0.31
PDE4A P27815 1/20 0.31
ADRA1A P35348 1/20 0.31
FDPS P14324 1/20 0.30
MEN1 O00255 1/20 0.30
MITF O75030 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10400022 0.88 SCN4A (0.34) SCN4APRCPMAPTGLI1HTR2C
SCHEMBL10610926 0.77 PRCP (0.39) PRCPMAPTHTR2CHTR2BLMNA
SCHEMBL4629689 0.75 SCN4A (0.43) SCN4APRCPGLI1
SCHEMBL11872839 0.75 PRCP (0.40) PRCPMAPTHTR2CHTR2BLMNA
SCHEMBL7299775 0.73 PRCP (0.42) SCN4APRCPMAPTHTR2CHTR2B
SCHEMBL31048387 0.73 PRCP (0.42) SCN4APRCPMAPTHTR2CHTR2B
SCHEMBL7298202 0.73 PRCP (0.42) SCN4APRCPMAPTHTR2CHTR2B
SCHEMBL8285912 0.71 PRCP (0.44) SCN4APRCPHTR2CHTR2BFDPS
SCHEMBL9040662 0.71 FDPS (0.42) PRCPMAPTHTR2CHTR2BLMNA
SCHEMBL10067945 0.71 PRCP (0.44) SCN4APRCPHTR2CHTR2BFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914092-A ANTIULCER AGENTS SYNTHELABO (FR) 1990-04-03 US disclosed