Phthalic Acid

Phthalic Acid

SCHEMBL10400552

CCC(CC)C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
ALOX15 P16050 1/20 0.58
POLB P06746 1/20 0.54
CYP1A2 P05177 1/20 0.52
FOLH1 Q04609 2/20 0.50
MAPT P10636 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA2 P00918 2/20 0.47
AKR1C3 P42330 2/20 0.47
MAPK1 P28482 1/20 0.47
KDM4E B2RXH2 2/20 0.45
CA12 O43570 2/20 0.45
CA9 Q16790 2/20 0.45
CA1 P00915 1/20 0.45
HMGB1 P09429 1/20 0.45
HPGD P15428 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL27649796 0.89 CA2 (0.67) ALDH1A1ALOX15POLBFOLH1MAPT
Phthalic Acid SCHEMBL6065205 0.83 ALDH1A1 (0.64) ALDH1A1ALOX15POLBCYP1A2MAPT
Phthalic Acid SCHEMBL27458631 0.82 ALDH1A1 (0.78) ALDH1A1ALOX15POLBMAPTHDAC8
Benzene SCHEMBL28308867 0.82 CA2 (0.64) ALDH1A1CYP1A2MAPTMEN1KMT2A
Phthalic Acid SCHEMBL29014247 0.82 ALDH1A1 (0.56) ALDH1A1ALOX15POLBMAPTHDAC8
Phthalic Acid SCHEMBL8577512 0.81 ALDH1A1 (0.61) ALDH1A1ALOX15POLBMAPTHDAC8
Toluene SCHEMBL3673405 0.81 CYP1A2 (0.54) ALDH1A1CYP1A2MAPTMEN1KMT2A
O-Xylene SCHEMBL29008699 0.81 CYP1A2 (0.54) ALDH1A1CYP1A2FOLH1MAPTMEN1
2-Ethylhexanoic Acid SCHEMBL23398208 0.81 CA2 (0.59) ALDH1A1POLBFOLH1MAPTMEN1
Phthalic Acid SCHEMBL9132518 0.80 ALDH1A1 (0.74) ALDH1A1ALOX15POLBMAPTHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102070456-B Method for preparing novel environmentally-friendly plasticizer WUXI WEIFENG CHEMICAL CO LTD 2013-11-27 CN disclosed
CN-102070456-A Method for preparing novel environmentally-friendly plasticizer WUXI WEIFENG CHEMICAL CO LTD 2011-05-25 CN disclosed
US-4893721-A Tamper-proof capsules WARNER-LAMBERT COMPANY (US) 1990-01-16 US disclosed
EP-0110500-B1 TAMPER-RESISTANT CAPSULES WARNER-LAMBERT COMPANY (US) 1987-06-03 EP disclosed
EP-0110500-A1 Tamper-resistant capsules WARNER-LAMBERT COMPANY (US) 1984-06-13 EP disclosed