SCHEMBL10401276

SCHEMBL10401276

CCCCOC(CCC)NC(CCC)OCCCC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
DNM1 Q05193 1/20 0.34
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11895439 0.93 DNM1 (0.42) DNM1TSHRALDH1A1
SCHEMBL9227236 0.83 ADRB2 (0.36) ADRB2ADRB1ADRB3DNM1CYP3A4
SCHEMBL8979936 0.77 DNM1 (0.41) DNM1TSHRALDH1A1
SCHEMBL8752660 0.76 DNM1 (0.43) DNM1ALDH1A1
SCHEMBL8752574 0.74 DNM1 (0.47) DNM1TSHR
SCHEMBL21796212 0.74 DNM1 (0.47) DNM1TSHR
SCHEMBL8752626 0.74 DNM1 (0.47) DNM1TSHR
SCHEMBL21796213 0.74 DNM1 (0.47) DNM1TSHR
SCHEMBL8752648 0.74 DNM1 (0.47) DNM1TSHR
SCHEMBL9229024 0.74 DNM1 (0.47) DNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399351-A2 Epoxy resin and water borne coatings therefrom THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed
US-4946911-A CONTAINING UNSATURATED IMIDE THE DOW CHEMICAL COMPANY (US) 1990-08-07 US disclosed
WO-1988003544-A1 AMIDE MODIFIED EPOXY RESINS THE DOW CHEMICAL COMPANY (US) 1988-05-19 WO disclosed
EP-0266694-A2 Amide modified epoxy resins THE DOW CHEMICAL COMPANY (US) 1988-05-11 EP disclosed
US-4721742-A Amide modified epoxy resins from a dialkanolamine, a monoalkanolamine, an anhydride and (an) unsaturated monomer(s) THE DOW CHEMICAL COMPANY (US) 1988-01-26 US disclosed