Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10401824 | 0.99 | ALDH1A1 (0.49) | ALDH1A1DRD2DRD3MAPTNPC1 | |
| SCHEMBL10401922 | 0.88 | MAPT (0.51) | ALDH1A1DRD2DRD3MAPTNPC1 | |
| SCHEMBL10401582 | 0.87 | TP53 (0.60) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL10401523 | 0.87 | ALDH1A1 (0.50) | ALDH1A1DRD2DRD3MAPTNPC1 | |
| SCHEMBL3043309 | 0.87 | GFER (0.55) | ALDH1A1DRD2DRD3MAPTNPC1 | |
| SCHEMBL10401849 | 0.87 | CHRM4 (0.54) | ALDH1A1DRD2MAPTHPGDLMNA | |
| SCHEMBL10401826 | 0.86 | DRD2 (0.62) | ALDH1A1DRD2DRD3MAPTUSP2 | |
| Hydrochloric Acid SCHEMBL10401376 | 0.86 | GFER (0.54) | ALDH1A1DRD2DRD3MAPTNPC1 | |
| SCHEMBL10401568 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNAPOLBTP53 | |
| Hydrochloric Acid SCHEMBL10401866 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |