Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401628 | 1.00 | MAPT (0.36) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10401766 | 0.83 | PPARD (0.33) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10404356 | 0.82 | MAOB (0.39) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10404355 | 0.82 | MAOB (0.39) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9868005 | 0.81 | MAPT (0.39) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9868008 | 0.81 | MAPT (0.39) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10404833 | 0.68 | KAT6A (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL10405477 | 0.68 | MEN1 (0.36) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10405675 | 0.67 | MEN1 (0.37) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10405674 | 0.67 | MEN1 (0.37) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978679-A | 6- and/or 7-substituted-1,2,3,4,4A,9B-hexahydro-8-hydroxydibenzofuran-3-ols as inhibitors of leukotriene biosynthesis | MERCK & CO., INC. (US) | 1990-12-18 | — | — | US | disclosed |