Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405674 | 0.90 | MEN1 (0.37) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10405675 | 0.90 | MEN1 (0.37) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10405373 | 0.87 | MTNR1A (0.37) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9868008 | 0.85 | MAPT (0.39) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9868005 | 0.85 | MAPT (0.39) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10405357 | 0.79 | CA12 (0.38) | MEN1LMNAKMT2ACA12CA1 | |
| SCHEMBL10401465 | 0.74 | CA12 (0.36) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10401481 | 0.73 | MAPT (0.37) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10401577 | 0.72 | MAPT (0.36) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10401766 | 0.70 | PPARD (0.33) | MEN1LMNAMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975457-A | Antiinflammatory agent; enzyme inhibitor | MERCK & CO., INC. (US) | 1990-12-04 | — | — | US | disclosed |