Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404356 | 1.00 | MAOB (0.39) | MAOBMAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10404833 | 0.83 | KAT6A (0.38) | MAOBMAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10401628 | 0.82 | MAPT (0.36) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10401630 | 0.82 | MAPT (0.36) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9868008 | 0.81 | MAPT (0.39) | MAOBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9868005 | 0.81 | MAPT (0.39) | MAOBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10401481 | 0.69 | MAPT (0.37) | MAOBMAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10401766 | 0.68 | PPARD (0.33) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10401577 | 0.68 | MAPT (0.36) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL16371575 | 0.68 | AOC3 (0.54) | MEN1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975457-A | Antiinflammatory agent; enzyme inhibitor | MERCK & CO., INC. (US) | 1990-12-04 | — | — | US | disclosed |