Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | NQO2 | P16083 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924906 | 1.00 | GLA (0.66) | GLANQO2RAB9ANPC1KDM4E | |
| SCHEMBL16070405 | 0.87 | GLA (0.72) | GLANQO2RAB9ANPC1KDM4E | |
| SCHEMBL31513649 | 0.86 | RAB9A (0.68) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL706942 | 0.86 | RAB9A (0.68) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL706943 | 0.86 | RAB9A (0.68) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL28439928 | 0.82 | GLA (0.75) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL28439930 | 0.82 | GLA (0.75) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL12884278 | 0.80 | RAB9A (0.73) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL10402225 | 0.80 | CYSLTR2 (0.77) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL10402227 | 0.80 | CYSLTR2 (0.77) | GLARAB9ANPC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962203-A | ANTIASTHMATIC, ANTIALLERGENIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS | MERCK FROST CANADA, INC. (CA) | 1990-10-09 | — | — | US | disclosed |
| EP-0206751-A2 | 2-Substituted quinolines, their preparation and use | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |