Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.58 |
| ▸ | TUBB | P07437 | 4/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439930 | 1.00 | GLA (0.75) | GLAAGTR1RAB9ANPC1TUBB4A | |
| SCHEMBL30442596 | 0.86 | GLA (1.00) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL29021873 | 0.86 | GLA (1.00) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL10924906 | 0.82 | GLA (0.66) | GLAAGTR1RAB9ANPC1TUBB4A | |
| SCHEMBL10401723 | 0.82 | GLA (0.66) | GLAAGTR1RAB9ANPC1TUBB4A | |
| SCHEMBL11062170 | 0.82 | GLA (0.78) | GLAAGTR1RAB9ANPC1KDM4E | |
| SCHEMBL10036065 | 0.82 | GLA (0.78) | GLAAGTR1RAB9ANPC1KDM4E | |
| SCHEMBL12281839 | 0.82 | AGTR1 (0.79) | GLAAGTR1RAB9ANPC1TUBB4A | |
| SCHEMBL28433890 | 0.80 | GLA (0.78) | GLARAB9ANPC1TUBB1KDM4E | |
| SCHEMBL28433887 | 0.80 | GLA (0.78) | GLARAB9ANPC1TUBB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494381-B | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-111494381-A | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2020-08-07 | — | — | CN | disclosed |