Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524766 | 0.88 | TSHR (0.47) | TSHRNPSR1PRCPEPHX2SCN9A | |
| SCHEMBL7694988 | 0.81 | TSHR (0.60) | TSHRNPSR1PRCPOPRM1SLC6A2 | |
| SCHEMBL30442509 | 0.81 | TSHR (0.60) | TSHRNPSR1PRCPOPRM1SLC6A2 | |
| SCHEMBL30829405 | 0.81 | TSHR (0.60) | TSHRNPSR1PRCPOPRM1SLC6A2 | |
| SCHEMBL9526040 | 0.79 | TSHR (0.42) | TSHRNPSR1PRCPEPHX2SCN9A | |
| SCHEMBL9524757 | 0.77 | TSHR (0.46) | TSHRNPSR1IDO1OPRM1SLC6A2 | |
| SCHEMBL10401735 | 0.75 | TSHR (0.44) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL18085727 | 0.75 | TSHR (0.65) | TSHRNPSR1PRCPOPRM1SLC6A2 | |
| SCHEMBL3609322 | 0.75 | TSHR (0.65) | TSHRNPSR1PRCPOPRM1SLC6A2 | |
| SCHEMBL31569203 | 0.75 | TSHR (0.65) | TSHRNPSR1PRCPOPRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |