Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401989 | 0.87 | TSHR (0.44) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL10402745 | 0.81 | HSD17B10 (0.43) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL10403103 | 0.80 | POLB (0.46) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL8436040 | 0.78 | GAA (0.74) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL10402744 | 0.78 | HSD17B10 (0.43) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL10401935 | 0.75 | POLB (0.44) | GAATSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1686848 | 0.74 | GAA (1.00) | GAAL3MBTL1TSHRPOLBALDH1A1 | |
| SCHEMBL14557231 | 0.74 | GAA (0.68) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL19369802 | 0.73 | POLB (0.53) | GAATSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9053674 | 0.73 | GAA (0.67) | GAAL3MBTL1TSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |