Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401989 | 0.83 | TSHR (0.44) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL10402744 | 0.78 | HSD17B10 (0.43) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL19369802 | 0.76 | POLB (0.53) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL10769958 | 0.76 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL10402745 | 0.74 | HSD17B10 (0.43) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL19361775 | 0.71 | POLB (0.48) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL10401935 | 0.71 | POLB (0.44) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL9840251 | 0.70 | POLB (0.47) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL8044327 | 0.69 | RXRA (0.41) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 | |
| SCHEMBL10403874 | 0.68 | POLB (0.44) | POLBSMN1; SMN2HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |