Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402600 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1ACEPOLBSMN1; SMN2 | |
| SCHEMBL10404382 | 0.89 | POLB (0.54) | KMT2AACEPOLBSMN1; SMN2LMNA | |
| SCHEMBL10404242 | 0.86 | FKBP1A (0.52) | L3MBTL1ACELMNACMA1 | |
| SCHEMBL10404111 | 0.84 | SMN1; SMN2 (0.64) | ACEPOLBSMN1; SMN2LMNALTA4H | |
| SCHEMBL15251748 | 0.82 | MEN1 (0.52) | KMT2AACEPOLBSMN1; SMN2LMNA | |
| SCHEMBL15252105 | 0.82 | MEN1 (0.52) | KMT2AACEPOLBSMN1; SMN2LMNA | |
| SCHEMBL15251747 | 0.82 | MEN1 (0.52) | KMT2AACEPOLBSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10403635 | 0.81 | FKBP1A (0.47) | ACELMNACMA1 | |
| Hydrochloric Acid SCHEMBL27870028 | 0.81 | F2 (0.46) | LMNACMA1 | |
| SCHEMBL15251960 | 0.81 | ACE (0.64) | KMT2AL3MBTL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | claimed |
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |