Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20484583 | 0.90 | POLB (0.54) | POLBSMN1; SMN2CMA1MEN1KMT2A | |
| SCHEMBL18620665 | 0.90 | POLB (0.54) | POLBSMN1; SMN2CMA1MEN1KMT2A | |
| SCHEMBL10402600 | 0.89 | KMT2A (0.54) | POLBSMN1; SMN2CMA1KMT2AACE | |
| SCHEMBL10402345 | 0.89 | KMT2A (0.54) | POLBSMN1; SMN2CMA1KMT2AACE | |
| SCHEMBL10404111 | 0.88 | SMN1; SMN2 (0.64) | POLBSMN1; SMN2ACELTA4HITGB3 | |
| SCHEMBL10403271 | 0.85 | FKBP1A (0.54) | CMA1ACEMMP13ADAMTS4ELANE | |
| SCHEMBL15251747 | 0.83 | MEN1 (0.52) | POLBSMN1; SMN2MEN1KMT2AACE | |
| SCHEMBL15251748 | 0.83 | MEN1 (0.52) | POLBSMN1; SMN2MEN1KMT2AACE | |
| SCHEMBL15252105 | 0.83 | MEN1 (0.52) | POLBSMN1; SMN2MEN1KMT2AACE | |
| SCHEMBL10402436 | 0.81 | POLB (0.49) | POLBSMN1; SMN2ACELTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | claimed |
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |