Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402401 | 0.87 | MTNR1A (0.33) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10405093 | 0.83 | HSD17B10 (0.32) | NPC1RAB9AALDH1A1HPGDMAPK1 | |
| SCHEMBL17788510 | 0.73 | HRH4 (0.33) | CYP1A2CYP2C19KDM4E | |
| SCHEMBL11521157 | 0.70 | KDM4E (0.30) | KDM4E | |
| SCHEMBL4318926 | 0.69 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL10403804 | 0.69 | — | — | |
| SCHEMBL10404354 | 0.69 | SMN1; SMN2 (0.37) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3090354 | 0.68 | CYP1A2 (0.34) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10402852 | 0.67 | HPGD (0.49) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6051456 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |