Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402402 | 0.83 | MTNR1A (0.36) | HPGDNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL11521157 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL10402401 | 0.72 | MTNR1A (0.33) | NPC1RAB9AALDH1A1 | |
| SCHEMBL10403804 | 0.71 | — | — | |
| SCHEMBL3090354 | 0.70 | CYP1A2 (0.34) | — | |
| SCHEMBL6051456 | 0.69 | — | — | |
| SCHEMBL10402933 | 0.67 | RPS6KA3 (0.33) | HSD17B10HPGDNPC1RAB9A | |
| SCHEMBL14220785 | 0.66 | — | — | |
| SCHEMBL9619930 | 0.64 | — | — | |
| SCHEMBL4318926 | 0.64 | MAPK1 (0.30) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |