SCHEMBL10403145

SCHEMBL10403145

OC(C=S)CNCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
ANPEP P15144 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
DNM1 Q05193 1/20 0.46
LMNA P02545 1/20 0.46
BCHE P06276 3/20 0.45
ADH1B P00325 1/20 0.42
ADH1C P00326 1/20 0.42
ADH1A P07327 1/20 0.42
ADH7 P40394 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
MAOA P21397 1/20 0.42
THRB P10828 1/20 0.42
IDO1 P14902 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10403337 0.83 ANPEP (0.53) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL1850858 0.81 ANPEP (0.47) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL5219600 0.80 ANPEP (0.46) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL1848295 0.79 ALDH1A1 (0.49) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL7095555 0.78 BCHE (0.60) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL7089480 0.78 BCHE (0.60) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL893963 0.78 BCHE (0.63) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL4154642 0.78 MEN1 (0.56) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
SCHEMBL10403019 0.78 MEN1 (0.47) ALDH1A1ANPEPCYP1A2CYP2D6MEN1
Hydrochloric Acid SCHEMBL11338579 0.76 ALDH1A1 (0.58) ALDH1A1ANPEPCYP1A2CYP2D6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0226896-A2 Lankacidin derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-07-01 EP disclosed