Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051118 | 0.92 | OPRD1 (0.47) | ANPEPALDH1A1CYP1A2CYP2D6DNM1 | |
| SCHEMBL6895986 | 0.87 | MEN1 (0.51) | ANPEPALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7118780 | 0.86 | BCHE (0.61) | MEN1KMT2ABCHE | |
| SCHEMBL28751162 | 0.85 | MEN1 (0.54) | ALDH1A1CYP1A2MEN1KMT2ALMNA | |
| SCHEMBL7054852 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL7053301 | 0.82 | LMNA (0.47) | ANPEPALDH1A1CYP1A2CYP2D6MEN1 | |
| SCHEMBL7054663 | 0.82 | DNM1 (0.55) | ALDH1A1DNM1MEN1KMT2ABCHE | |
| SCHEMBL10403337 | 0.81 | ANPEP (0.53) | ANPEPALDH1A1CYP1A2CYP2D6DNM1 | |
| SCHEMBL5391447 | 0.81 | ABCB1 (0.46) | ANPEPCYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL4045031 | 0.81 | KDM1A (0.46) | MEN1KMT2ALMNABCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |