Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403230 | 0.89 | GAA (0.54) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL10404173 | 0.83 | GAA (0.64) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL10401909 | 0.77 | KDM4E (0.41) | GAAL3MBTL1APEX1ALDH1A1HPGD | |
| SCHEMBL22051693 | 0.77 | GAA (0.59) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL10402167 | 0.77 | ALOX5 (0.40) | GAAHTTAPEX1ALDH1A1NPC1 | |
| SCHEMBL1686848 | 0.75 | GAA (1.00) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL10402042 | 0.75 | GAA (0.73) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL10404083 | 0.75 | GAA (0.62) | GAAL3MBTL1POLBHTTAPEX1 | |
| SCHEMBL10404171 | 0.75 | GAA (0.57) | GAAL3MBTL1POLBHTTTSHR | |
| SCHEMBL13240158 | 0.73 | GAA (0.59) | GAAL3MBTL1POLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |