Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402166 | 0.89 | ALOX5 (0.39) | ALOX5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL10403521 | 0.85 | ALOX5 (0.39) | ALOX5ALDH1A1HSD17B10APEX1NPC1 | |
| SCHEMBL10968557 | 0.80 | APEX1 (0.47) | ALDH1A1HSD17B10APEX1NPC1RAB9A | |
| SCHEMBL13277864 | 0.77 | GAA (0.56) | ALDH1A1HSD17B10RAB9AMAPTGAA | |
| SCHEMBL10402728 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HTR7APEX1NPC1 | |
| SCHEMBL10403231 | 0.77 | GAA (0.60) | ALDH1A1APEX1NPC1RAB9AMAPT | |
| SCHEMBL10403518 | 0.77 | ALOX5 (0.38) | ALOX5ALDH1A1HSD17B10NPC1PKM | |
| SCHEMBL10770339 | 0.75 | ALDH1A1 (0.41) | ALOX5ALDH1A1MTNR1AMTNR1BNPC1 | |
| SCHEMBL13471446 | 0.75 | MAPT (0.42) | ALDH1A1HSD17B10NPC1RAB9AMAPT | |
| SCHEMBL15832742 | 0.73 | HTR7 (0.37) | ALDH1A1HSD17B10HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |