Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202099 | 0.90 | CHRM1 (0.67) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL23881501 | 0.90 | CHRM1 (0.67) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11874459 | 0.79 | CHRM1 (0.58) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL10403001 | 0.77 | CHRM1 (0.50) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7324283 | 0.77 | CHRM1 (0.73) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL23881527 | 0.77 | CHRM1 (0.77) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL7322840 | 0.77 | CHRM1 (0.77) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11837213 | 0.76 | ADRA1A (0.60) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL11868671 | 0.76 | CHRM1 (0.61) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL23927137 | 0.75 | CHRM1 (0.45) | CHRM1GABRA1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902794-A | Triazolo-benzodiazepines | THE UPJOHN COMPANY (US) | 1990-02-20 | — | — | US | disclosed |