Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765880 | 0.98 | LMNA (0.52) | LMNAMAPTMAPK1CYP19A1ALDH1A1 | |
| SCHEMBL491457 | 0.93 | LMNA (0.47) | LMNAMAPTMAPK1CYP19A1ALDH1A1 | |
| SCHEMBL10456217 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9622733 | 0.90 | LMNA (0.47) | LMNAMAPTMAPK1CYP19A1ALDH1A1 | |
| SCHEMBL6652791 | 0.90 | TSHR (0.47) | LMNACYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL8419684 | 0.90 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9885357 | 0.88 | CYP19A1 (0.48) | LMNACYP19A1TSHR | |
| SCHEMBL23754243 | 0.87 | LMNA (0.42) | LMNAMAPTMAPK1CYP19A1ALDH1A1 | |
| SCHEMBL22248495 | 0.87 | LMNA (0.57) | LMNAMAPTMAPK1CYP19A1ALDH1A1 | |
| SCHEMBL569772 | 0.85 | LMNA (0.71) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968453-A | FOR AUTOMOBILE SUPERCHARGER | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1990-11-06 | — | — | US | disclosed |
| US-4719025-A | WEAR RESISTANCE, DIESTER, POLYETHER | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1988-01-12 | — | — | US | disclosed |