Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403448 | 0.98 | LMNA (0.55) | LMNACYP19A1MAPTMAPK1ALDH1A1 | |
| SCHEMBL491457 | 0.95 | LMNA (0.47) | LMNACYP19A1MAPTMAPK1ALDH1A1 | |
| SCHEMBL8419684 | 0.92 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL6652791 | 0.92 | TSHR (0.47) | LMNACYP19A1ALDH1A1TSHRMEN1 | |
| SCHEMBL9885357 | 0.90 | CYP19A1 (0.48) | LMNACYP19A1TSHR | |
| SCHEMBL10456217 | 0.90 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL23754243 | 0.89 | LMNA (0.42) | LMNACYP19A1MAPTMAPK1ALDH1A1 | |
| SCHEMBL22248495 | 0.89 | LMNA (0.57) | LMNACYP19A1MAPTMAPK1ALDH1A1 | |
| SCHEMBL9622733 | 0.88 | LMNA (0.47) | LMNACYP19A1MAPTMAPK1ALDH1A1 | |
| SCHEMBL28795594 | 0.87 | TSHR (0.52) | LMNACYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064082-B1 | CONTAMINANT DISPERSANTS USEFUL IN RECYCLING OF TREATED CONTAINERS | NALCO CO (US) | 2004-06-02 | — | — | EP | claimed |
| US-6113738-A | ADDING PLASTICIZER SELECTED FROM ADIPIC ACID, DIMETHYL ADIPATE, DIETHYL ADIPATE, DIISOBUTYL ADIPATE AND OTHER ESTERS OF ADIPIC ACID; DISPERSING TO OBTAIN TREATED FIBER; SEPARATING TREATED FIBER FROM SLURRY CONTAINING WAX; RECOVERING FIBER | NALCO CHEMICAL COMPANY (US) | 2000-09-05 | — | — | US | claimed |
| US-8207098-B2 | Lubricant additive, lubricant composition and grease composition | YAMANASHI UNIVERSITY (JP) | 2012-06-26 | — | — | US | disclosed |
| WO-2007018394-A9 | HIGHLY ELASTIC POLYVINYL CHLORIDE COMPOSITION AND PRODUCTS PREPARED USING THE SAME | LG CHEM, LTD. (KR) | 2010-12-02 | — | — | WO | disclosed |
| US-20090239773-A1 | LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION | YAMANASHI UNIVERSITY (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1913081-A1 | HIGHLY ELASTIC POLYVINYL CHLORIDE COMPOSITION AND PRODUCTS PREPARED USING THE SAME | LG Chem. Ltd. (KR) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018394-A1 | HIGHLY ELASTIC POLYVINYL CHLORIDE COMPOSITION AND PRODUCTS PREPARED USING THE SAME | LG CHEM, LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |
| US-20070037929-A1 | Highly elastic polyvinyl chloride composition and products prepared using the same | LG CHEM, LTD (KR) | 2007-02-15 | — | — | US | disclosed |
| EP-1064082-B1 | CONTAMINANT DISPERSANTS USEFUL IN RECYCLING OF TREATED CONTAINERS | NALCO CO (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6548558-B2 | Reuse of paper, paperboard | ONDEO NALCO COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-20010041749-A1 | Contaminant dispersants useful in recycling of treated containers | ECOLAB USA INC. | 2001-11-15 | — | — | US | disclosed |
| EP-1064082-A4 | CONTAMINANT DISPERSANTS USEFUL IN RECYCLING OF TREATED CONTAINERS | NALCO CHEMICAL CO (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1064082-A1 | CONTAMINANT DISPERSANTS USEFUL IN RECYCLING OF TREATED CONTAINERS | NALCO CHEMICAL COMPANY (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6113738-A | ADDING PLASTICIZER SELECTED FROM ADIPIC ACID, DIMETHYL ADIPATE, DIETHYL ADIPATE, DIISOBUTYL ADIPATE AND OTHER ESTERS OF ADIPIC ACID; DISPERSING TO OBTAIN TREATED FIBER; SEPARATING TREATED FIBER FROM SLURRY CONTAINING WAX; RECOVERING FIBER | NALCO CHEMICAL COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999047248-A1 | CONTAMINANT DISPERSANTS USEFUL IN RECYCLING OF TREATED CONTAINERS | NALCO CHEMICAL COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| EP-0578435-B1 | Friction modification of synthetic gear oils | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0767236-A1 | Friction modification of synthetic gear oils | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| EP-0578435-A1 | Friction modification of synthetic gear oils | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1994-01-12 | — | — | EP | disclosed |
| US-4968453-A | FOR AUTOMOBILE SUPERCHARGER | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1990-11-06 | — | — | US | disclosed |
| US-4719025-A | WEAR RESISTANCE, DIESTER, POLYETHER | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1988-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239773-A1 | LUBRICANT ADDITIVE, LUBRICANT COMPOSITION AND GREASE COMPOSITION | GRN, GRIA1, GRIK5 | LMNA 3546/4885CYP19A1 3495/4885MAPT 2509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.