Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856146 | 0.83 | PPARG (0.52) | PPARGALOX5PPARAMMP9MMP13 | |
| SCHEMBL8356987 | 0.80 | PPARG (0.64) | PPARGALOX5PPARAPTGES | |
| SCHEMBL9099036 | 0.80 | PPARG (0.64) | PPARGALOX5PPARAPTGES | |
| SCHEMBL9099026 | 0.80 | PPARG (0.64) | PPARGALOX5PPARAPTGES | |
| SCHEMBL22612343 | 0.80 | PPARG (0.64) | PPARGALOX5PPARAPTGES | |
| SCHEMBL5081085 | 0.78 | PPARG (0.66) | PPARGALOX5PPARAPTGES | |
| SCHEMBL5080497 | 0.73 | PPARG (0.72) | PPARGALOX5PPARAPTGES | |
| SCHEMBL28567055 | 0.73 | TSHR (0.44) | PPARGALOX5PPARAPTGESALDH1A1 | |
| SCHEMBL9714658 | 0.73 | PPARG (0.44) | PPARGALOX5PPARAPTGESALDH1A1 | |
| SCHEMBL22042316 | 0.72 | PPARG (0.49) | PPARGALOX5PPARAPTGESLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966916-A | DI-AND TRIMETHYLAMINOETHYL BENZOATES, PHENYLCARBAMATES AND PHENYLTHIOCARBAMATES | UNIVERSITY OF ROCHESTER | 1990-10-30 | — | — | US | claimed |