Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.53 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404568 | 0.92 | ACE (0.53) | FKBP1AACEF10CTRB1F2 | |
| SCHEMBL10404429 | 0.90 | FKBP1A (0.50) | FKBP1AACEF10F2PLG | |
| SCHEMBL15251676 | 0.90 | FKBP1A (0.52) | FKBP1AACE | |
| SCHEMBL15251677 | 0.90 | FKBP1A (0.52) | FKBP1AACE | |
| SCHEMBL10404430 | 0.88 | F10 (0.49) | FKBP1AACEF10F2PLG | |
| SCHEMBL10403978 | 0.87 | FKBP1A (0.48) | FKBP1AACECTRB1 | |
| SCHEMBL10404990 | 0.87 | FKBP1A (0.50) | FKBP1AACEF10ALDH1A1 | |
| SCHEMBL15251894 | 0.87 | FKBP1A (0.56) | FKBP1AACEF10F2PLG | |
| SCHEMBL10403271 | 0.85 | FKBP1A (0.54) | FKBP1AACECYP3A4TSHRALDH1A1 | |
| SCHEMBL10402436 | 0.85 | POLB (0.49) | ACETSHRF10F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |