Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.54 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404242 | 0.92 | FKBP1A (0.52) | FKBP1ACMA1ACETSHR | |
| SCHEMBL15251677 | 0.87 | FKBP1A (0.52) | FKBP1AACE | |
| SCHEMBL15251676 | 0.87 | FKBP1A (0.52) | FKBP1AACE | |
| Hydrochloric Acid SCHEMBL10403635 | 0.86 | FKBP1A (0.47) | FKBP1ACMA1ACECYP3A4TSHR | |
| SCHEMBL10404568 | 0.85 | ACE (0.53) | FKBP1AADAMTS4ACE | |
| SCHEMBL10403953 | 0.85 | FKBP1A (0.53) | FKBP1AACEALDH1A1CYP3A4TSHR | |
| SCHEMBL10404382 | 0.85 | POLB (0.54) | CMA1ADAMTS4MMP13ACEELANE | |
| SCHEMBL15251894 | 0.84 | FKBP1A (0.56) | FKBP1AACE | |
| SCHEMBL1992452 | 0.83 | FKBP1A (0.60) | FKBP1ACMA1ELANEPREPALDH1A1 | |
| SCHEMBL10404429 | 0.83 | FKBP1A (0.50) | FKBP1AADAMTS4MMP13ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |