Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404263 | 0.84 | POLB (0.35) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL24457797 | 0.83 | POLB (0.40) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL16808292 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL10265114 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL7828421 | 0.81 | ATM (0.42) | POLBKMT2AMEN1CCKBRMAPT | |
| SCHEMBL8597022 | 0.81 | ATM (0.42) | POLBKMT2AMEN1CCKBRMAPT | |
| SCHEMBL10404091 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBKMT2AMEN1MAPT | |
| Water SCHEMBL8600954 | 0.81 | ATM (0.42) | POLBKMT2AMEN1CCKBRMAPT | |
| SCHEMBL10205157 | 0.81 | KMT2A (0.49) | ALDH1A1POLBKMT2AMAPTNPC1 | |
| SCHEMBL8626971 | 0.80 | POLB (0.38) | ALDH1A1POLBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |