Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342217 | 0.88 | HMGCR (0.46) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL39364 | 0.87 | HMGCR (0.62) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL564169 | 0.86 | HMGCR (0.61) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL28615117 | 0.86 | HMGCR (0.61) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL5428580 | 0.86 | HMGCR (0.61) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL562987 | 0.86 | HMGCR (0.61) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL39365 | 0.84 | LMNA (0.46) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL859105 | 0.82 | HMGCR (0.59) | HMGCRNR1I2GAAKMT2AMEN1 | |
| Tetrylammonium SCHEMBL276752 | 0.81 | HMGCR (0.56) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL10992943 | 0.80 | HMGCR (0.58) | HMGCRNR1I2GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263764-A1 | CYCLIC PHOSPHINES AS FLAME RETARDANTS | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110214590-A1 | STABILISERS FOR INANIMATE ORGANIC MATERIALS | BASF SE (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20110028603-A1 | HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS | BASF SE (DE) | 2011-02-03 | — | — | US | disclosed |
| WO-2011009876-A1 | DERIVATIVES OF DIPHOSPHINES AS FLAME RETARDANTS IN AROMATIC AND/OR HETEROAROMATIC EPOXY RESINS | BASF SE (DE) | 2011-01-27 | — | — | WO | disclosed |
| US-7714044-B2 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BASF AKITENGESELLSCHAFT (DE) | 2010-05-11 | — | — | US | disclosed |
| US-20070100033-A1 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BAST AKTIENGESELLSCHAFT (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110214590-A1 | STABILISERS FOR INANIMATE ORGANIC MATERIALS | C1S, C1R, F12 | HMGCR 1082/4885NR1I2 1894/4885GAA 3132/4885 |
| US-20110263764-A1 | CYCLIC PHOSPHINES AS FLAME RETARDANTS | PFAS, PHOSPHO1, PLCG2 | HMGCR 4329/4885NR1I2 2387/4885GAA 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.