Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970072 | 0.82 | CA1 (0.60) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8246439 | 0.80 | SMN1; SMN2 (0.53) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL6992440 | 0.78 | TP53 (0.40) | ALDH1A1GAANPC1RAB9AMAPT | |
| SCHEMBL9360322 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAANPC1RAB9AKMT2A | |
| SCHEMBL10990096 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10404147 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11327057 | 0.76 | CA12 (0.62) | ALDH1A1HSD17B10MAPTSMN1; SMN2POLB | |
| SCHEMBL11424630 | 0.76 | SMN1; SMN2 (0.49) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL11090182 | 0.76 | CA1 (0.37) | KMT2ASMN1; SMN2TP53TSHRGLS | |
| SCHEMBL11516768 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |