Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA11 | O75493 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090182 | 0.81 | CA1 (0.37) | TP53SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL8246439 | 0.81 | SMN1; SMN2 (0.53) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL12346979 | 0.78 | TP53 (0.44) | TP53SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9360322 | 0.78 | ALDH1A1 (0.39) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10404148 | 0.78 | KDM4E (0.53) | TP53SMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL8626453 | 0.77 | POLB (0.60) | SMN1; SMN2MAPTALDH1A1TDP1POLB | |
| SCHEMBL14582747 | 0.76 | TP53 (0.43) | TP53SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL11516768 | 0.76 | ALDH1A1 (0.38) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL11559131 | 0.76 | TP53 (0.66) | TP53SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL2664519 | 0.76 | SMN1; SMN2 (0.67) | TP53SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671892-A | 7-aminocephalosporanic acid-containing 1,3, 4-thiadiazole derivative, and preparation method and application thereof | 江苏海洋大学 | 2022-06-28 | — | — | CN | disclosed |
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |