Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.34 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700472 | 0.77 | GABRA1 (0.43) | TRIM24TRIM33HPGDCYP11B1CYP11B2 | |
| SCHEMBL1807157 | 0.75 | SLC6A4 (0.40) | TRIM24TRIM33 | |
| SCHEMBL27865426 | 0.75 | TRIM24 (0.41) | TRIM24TRIM33S1PR4HPGDSMN1; SMN2 | |
| SCHEMBL16838712 | 0.74 | TRIM24 (0.43) | TRIM24TRIM33S1PR4SMN1; SMN2CYP11B1 | |
| SCHEMBL29743319 | 0.74 | TRIM24 (0.43) | TRIM24TRIM33S1PR4SMN1; SMN2CYP11B1 | |
| SCHEMBL23489987 | 0.73 | TRIM24 (0.39) | TRIM24TRIM33HPGDSMN1; SMN2CYP11B1 | |
| SCHEMBL20832103 | 0.73 | CYP1A2 (0.39) | TRIM24TRIM33HPGDSMN1; SMN2CYP11B1 | |
| SCHEMBL3101566 | 0.73 | TRIM24 (0.39) | TRIM24TRIM33HPGDSMN1; SMN2CYP11B1 | |
| SCHEMBL30320666 | 0.73 | TRIM24 (0.39) | TRIM24TRIM33HPGDSMN1; SMN2CYP11B1 | |
| SCHEMBL26271973 | 0.73 | TRIM24 (0.39) | TRIM24TRIM33HPGDSMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952602-A | TREATMENT OF ARTERIOSCLEROSIS | TANABE SEIYAKU COMPANY, LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0316939-A2 | Biphenyl derivatives, preparation method, pharmaceutical compositions comprising them and use | Tanabe Seiyaku Co., Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |