SCHEMBL30320666

SCHEMBL30320666

CC(O)c1cccnc1Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
SLC40A1 Q9NP59 1/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
HIF1A Q16665 2/20 0.33
CYP2C19 P33261 1/20 0.33
GAA P10253 2/20 0.33
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23489987 1.00 TRIM24 (0.39) TRIM24TRIM33SLC40A1GABRA1GABRB2
SCHEMBL3101566 1.00 TRIM24 (0.39) TRIM24TRIM33SLC40A1GABRA1GABRB2
SCHEMBL20818220 0.84 TRIM24 (0.37) TRIM24TRIM33GABRA1GABRB2MMP2
SCHEMBL5263705 0.84 PPARA (0.32) TRIM24TRIM33SLC40A1MMP2MMP9
SCHEMBL15532406 0.83 SLC40A1 (0.40) TRIM24TRIM33SLC40A1GABRA1GABRB2
SCHEMBL5700472 0.83 GABRA1 (0.43) TRIM24TRIM33SLC40A1GABRA1GABRB2
SCHEMBL27865426 0.81 TRIM24 (0.41) TRIM24TRIM33GABRA1GABRB2MMP2
SCHEMBL20832103 0.79 CYP1A2 (0.39) TRIM24TRIM33GABRA1GABRB2CYP2C19
SCHEMBL26271973 0.79 TRIM24 (0.39) TRIM24TRIM33GABRA1GABRB2CYP2C19
SCHEMBL20818031 0.79 LMNA (0.39) TRIM24TRIM33HIF1ACYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528915-A Compounds for inhibiting apoptosis and methods of making the same 中国科学院上海有机化学研究所 2025-02-28 CN disclosed
CN-115806557-B Compounds for inhibiting apoptosis and methods of making the same 中国科学院上海有机化学研究所 2025-02-14 CN disclosed
CN-115806557-A Compound for inhibiting programmed cell death and preparation method thereof 中国科学院上海有机化学研究所 2023-03-17 CN disclosed