Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665783 | 0.85 | ALDH1A1 (0.46) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL10403022 | 0.84 | CYP19A1 (0.41) | CYP1A2ALDH1A1CYP2C9CYP2C19TSHR | |
| SCHEMBL7172957 | 0.83 | CTSC (0.47) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL4306985 | 0.83 | ALDH1A1 (0.44) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL31553563 | 0.78 | ALDH1A1 (0.53) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL10404049 | 0.77 | PTPRA (0.48) | CYP1A2ALDH1A1PTGS1KDM4EMAPT | |
| SCHEMBL9028692 | 0.77 | ALDH1A1 (0.52) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL3505882 | 0.77 | ALDH1A1 (0.52) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL5617244 | 0.77 | ALDH1A1 (0.52) | CYP1A2ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL11212905 | 0.77 | TAAR1 (0.42) | CYP1A2ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |