Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996284 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL27559513 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL4996289 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL10405242 | 0.86 | CYP19A1 (0.48) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL10405243 | 0.86 | CYP19A1 (0.48) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL31164338 | 0.86 | CYP19A1 (0.48) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL14677734 | 0.82 | SERPINA6 (0.50) | SHBGMAPK1POLBLMNAHSD17B10 | |
| SCHEMBL21807731 | 0.81 | CYP19A1 (0.54) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL10402803 | 0.81 | SHBG (0.60) | CYP19A1SHBGMAPK1POLBLMNA | |
| SCHEMBL497738 | 0.81 | CYP19A1 (0.54) | CYP19A1SHBGMAPK1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |